Destructive Impact of Cyanotoxins on Human Health: Examining Real-Life Tragic Outcomes

Cyanotoxins are toxic substances produced by cyanobacteria, or blue-green algae, which can proliferate in water bodies under conditions like high nutrient levels and warm temperatures. There are over 1,118 different cyanotoxins identified globally in freshwater environments across 66 countries, illustrating the widespread nature of this issue.

Cyanobacteria, or blue-green algae, under a microscope

These toxins can contaminate drinking water, recreational waters, and seafood, posing serious risks to human health. In severe cases, exposure to cyanotoxins can even be fatal.

A pond covered in blue-green algae or cyanobacteria, surrounded by trees under a clear blue sky.

Examining Two Tragic Cases of Cyanotoxin-Induced Deaths in Brazil

The catastrophic effects of cyanotoxins on human health are not theoretical; they have resulted in real tragedies. Here, we explore two poignant examples from Brazil where cyanotoxin exposure led to loss of life, highlighting the urgent need for effective monitoring and intervention strategies.

The 1996 hemodialysis tragedy in Caruaru, Pernambuco, starkly underscores the critical need for safe water in medical settings. Contaminated water used in hemodialysis led to severe infections and fatalities, revealing flaws in both water purification systems and quality control.

Closeup of dialysis machine and chair

Due to the presence of cyanotoxins in water from a local treatment plant, 52 out of 131 hemodialysis patients lost their lives. The investigation identified microcystin, a dangerous toxin from cyanobacteria, as the cause, highlighting the severe risks posed by inadequate water treatment.

Another incident in Brazil has been linked to 2,000 cases of gastroenteritis and 88 deaths caused by algal blooms. This outbreak occurred in the Paulo Afonso region of Bahia State following the flooding of the newly constructed Itaparica Dam’s reservoir in 1988.

The conditions in the dam’s reservoir, such as decomposing biomass, encouraged the growth of cyanobacteria. Investigations found that toxins from these cyanobacteria caused the epidemic.

Major Cyanotoxins and Their Impacts on Human Health

Cyanotoxins enter the human body primarily through ingestion, inhalation, or direct skin contact with contaminated water or food. People can be exposed by drinking water containing cyanotoxins, consuming fish or shellfish from affected waters, or inhaling aerosols while swimming or showering in contaminated water.

The health effects of cyanotoxins vary based on the type of toxin, the level of exposure, and the route of entry. Among the over 1,000 identified cyanotoxins, the following are particularly notable due to their severe health impacts and common occurrence in harmful algal blooms.

1. Microcystins 

  • Source: Produced by cyanobacteria such as Microcystis.

  • Health Impacts: Microcystins primarily target the liver, causing damage that can lead to hepatitis, cirrhosis, and potentially liver cancer. Symptoms of exposure include gastrointestinal distress like nausea and diarrhea.

  • Additional Concerns: Long-term exposure to microcystins can have chronic health effects and increase the risk of liver cancer.

2. Anatoxins

  • Source: Found in cyanobacteria such as Anabaena and Planktothrix.

  • Health Impacts: Anatoxins are neurotoxins that can cause respiratory paralysis, convulsions, and death if ingested in large amounts. They affect nerve signal transmission, leading to muscle paralysis and respiratory failure.

  • Additional Concerns: High exposure risks for both humans and animals, particularly through contaminated water sources.

3. Saxitoxins 

  • Source: Produced by some freshwater cyanobacteria and marine dinoflagellates.

  • Health Impacts: Saxitoxins cause Paralytic Shellfish Poisoning (PSP), which can result in numbness, dizziness, and in severe cases, respiratory failure and death. Symptoms start with tingling sensations and can progress to paralysis.

  • Additional Concerns: These toxins bioaccumulate in shellfish, presenting risks to humans consuming contaminated seafood.

4. Cylindrospermopsin

  • Source: Produced by cyanobacteria like Cylindrospermopsis and Aphanizomenon.

  • Health Impacts: Cylindrospermopsin is a hepatotoxin and cytotoxin that damages the liver and kidneys, causing symptoms such as gastrointestinal distress and organ failure.

  • Additional Concerns: Disrupts aquatic ecosystems by affecting biodiversity and causing stress to aquatic organisms.

5. Nodularins

  • Source: Produced by cyanobacteria such as Nodularia.

  • Health Impacts: Nodularins are structurally similar to microcystins and also primarily affect the liver. They can cause liver damage, leading to hepatitis, liver tumors, and potentially liver failure. Symptoms may include nausea, vomiting, and abdominal pain.

  • Additional Concerns: Long-term exposure can increase the risk of liver cancer and contribute to chronic liver diseases.

Managing Cyanotoxins and Protecting Water Quality

Cyanotoxins represent a serious and growing threat to global health and ecosystems. By understanding their impacts and taking proactive measures to manage and mitigate these risks, we can better safeguard public health and preserve our environmental resources. Water treatment facilities in particular must prioritize the detection and removal of cyanobacteria and its toxins to ensure community health and prevent potentially deadly risks.

LG Sonic plays a crucial role in the mitigation and management of cyanobacteria through the use of ultrasonic technology. Our algae control devices emit sound waves that disrupt the buoyancy and photosynthesis of cyanobacteria. LG Sonic’s technology predicts and prevents algal blooms from forming and minimizes the need for chemicals in the water treatment process.

LG Sonic's algae control device deployed in water, showing ultrasound frequencies emitted underwater

This environmentally friendly approach is effective in large water bodies like drinking water reservoirs and lakes. By targeting the root cause of blooms, LG Sonic helps restore and maintain water quality while protecting aquatic ecosystems from the harmful effects of cyanobacteria.

Given the severe risks of these toxins, it’s crucial to monitor water quality closely and ensure effective purification, especially in sensitive areas like drinking water reservoirs. Stricter regulations and coordinated efforts among stakeholders are essential to minimizing exposure and protecting public health and the environment from these potent toxins.